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The 1st asymmetric whole synthesis of conolidine was designed by Micalizio and coworkers in 2011.[2] This artificial route will allow usage of both enantiomer (mirror image) of conolidine through an early enzymatic resolution."We confirmed that conolidine binds into the newly identified opioid receptor ACKR3, when showing no affinity for the other
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This is often an open-accessibility report dispersed beneath the conditions with the Innovative Commons Attribution-NonCommercial four.0 Worldwide License () which permits duplicate and redistribute the fabric just in noncommercial usages, supplied the original perform is correctly cited.Conolidine CONOCB2™, which has been code-named 'natures mor